By Dr. Mercola
The true toxicity of glyphosate—the active ingredient in Monsanto’s broad-spectrum herbicide Roundup—is becoming increasingly clear as study after study is published demonstrating its devastating effects. In June, groundbreaking research was published detailing a newfound mechanism of harm for Roundup.This was immediately followed by tests showing that people in 18 countries across Europe have glyphosate in their bodies,1 while yet another study revealed that the chemical has estrogenic properties and drives breast cancer proliferation in the parts-per-trillion range.2This finding might help explain why rats fed Monsanto’s maize developed massive breast tumors in the first-ever lifetime feeding study published last year. Other recently published studies demonstrate glyphosate’s toxicity to cell lines, aquatic life, food animals, and humans.
Glyphosate Toxicity Underestimated, Study Concludes
One such study, published in the journal Ecotoxicology,3 found that glyphosate is toxic to water fleas (Daphnia magna) at minuscule levels that are well within the levels expected to be found in the environment.According to regulators, glyphosate is thought to be practically nontoxic to aquatic invertebrates. The water flea is a widely accepted model for environmental toxicity, so this study throws serious doubt on glyphosate’s classification as environmentally safe. According to the study:“To test the acute effects of both glyphosate and a commercial formulation of Roundup (hereafter Roundup), we conducted a series of exposure experiments with different clones and age-classes of D. magna.... Roundup showed slightly lower acute toxicity than glyphosate IPA alone... However, in chronic toxicity tests spanning the whole life-cycle, Roundup was more toxic....Significant reduction of juvenile size was observed even in the lowest test concentrations of 0.05 mg a.i./l, for both glyphosate and Roundup. At 0.45 mg a.i./l, growth, fecundity and abortion rate was affected, but only in animals exposed to Roundup.At 1.35 and 4.05 mg a.i./l of both glyphosate and Roundup, significant negative effects were seen on most tested parameters, including mortality. D. magna was adversely affected by a near 100% abortion rate of eggs and embryonic stages at 1.35 mg a.i./l of Roundup.The results indicate that aquatic invertebrate ecology can be adversely affected by relevant ambient concentrations of this major herbicide. We conclude that glyphosate and Roundup toxicity to aquatic invertebrates have been underestimated and that current European Commission and US EPA toxicity classification of these chemicals need to be revised.”
Herbicide Formulations Far More Toxic Than Glyphosate Alone
An article published on Greenmedinfo.com4 last year reviewed several interesting studies relating to the profound toxicity of Monsanto’s herbicide Roundup:“Back in Feb. of 2012, the journal Archives of Toxicology5 published a shocking study showing that Roundup is toxic to human DNA even when diluted to concentrations 450-fold lower than used in agricultural applications.This effect could not have been anticipated from the known toxicological effects of glyphosate alone. The likely explanation is that the surfactant polyoxyethyleneamine within Roundup dramatically enhances the absorption of glyphosate into exposed human cells and tissue,” Sayer Ji writes.“If this is true, it speaks to a fundamental problem associated with toxicological risk assessments of agrichemicals (and novel manmade chemicals in general), namely, these assessments do not take into account the reality of synergistic toxicologies, i.e. the amplification of harm associated with multiple chemical exposures occurring simultaneously.”
'Inert' Ingredients Does NOT Mean They Are Inactive...
Similarly, another study published that year in the journal Toxicology6, 7 revealed that inert ingredients such as solvents, preservatives, surfactants and other added substances are anything but “inactive.” They in fact contribute to toxicity in a synergistic manner, and ethoxylated adjuvants in glyphosate-based herbicides were found to be "active principles of human cell toxicity."(On a side note, an “ethoxylated” compound is a chemical that has been produced using the carcinogen ethylene oxide.8 The ethoxylation process also produces the carcinogenic byproduct 1,4-dioxane. It’s also worth noting here that the term “inert ingredient” does NOT actually mean that it is biologically or toxicologically harmless! When you see “inert” or “inactive ingredients” listed on the label of a pesticide or herbicide, it only means that those ingredients will not harm pests or weeds. This is how federal law classifies “inert” pesticide ingredients.)9The study found that liver, embryonic and placental cell lines exposed to various herbicide formulations for 24 hours at doses as low as 1 part per million (ppm), had adverse effects.10 According to the authors:11“Here we demonstrate that all formulations are more toxic than glyphosate, and we separated experimentally three groups of formulations differentially toxic according to their concentrations in ethoxylated adjuvants. Among them, POE-15 clearly appears to be the most toxic principle against human cells, even if others are not excluded. It begins to be active with negative dose-dependent effects on cellular respiration and membrane integrity between 1 and 3ppm, at environmental/occupational doses. We demonstrate in addition that POE-15 induces necrosis when its first micellization process occurs, by contrast to glyphosate which is known to promote endocrine disrupting effects after entering cells.Altogether, these results challenge the establishment of guidance values such as the acceptable daily intake of glyphosate, when these are mostly based on a long term in vivo test of glyphosate alone. Since pesticides are always used with adjuvants that could change their toxicity, the necessity to assess their whole formulations as mixtures becomes obvious. This challenges the concept of active principle of pesticides for non-target species.” [Emphasis mine]Perhaps most disturbing of all, the researchers claim that cell damage and even cell death can occur at the residual levels found on Roundup-treated crops, as well as lawns and gardens where Roundup is applied for weed control. They also suspect that:12“Roundup might cause pregnancy problems by interfering with hormone production, possibly leading to abnormal fetal development, low birth weights or miscarriages.”
http://articles.mercola.com/sites/articles/archive/2013/07/30/glyphosate-toxicity.aspx Read more on this at Mercola.com website.
You have to love these people. You can not kill them but they can kill you? How nice.
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